Microfluidic Chip Manufacturer

Microfluidic chips are categorized by their method of fluid handling, such as continuous-flow or digital (droplet-based), and by their function, including organ-on-a-chip, cell sorters, mixers, and paper-based devices for diagnostics. They can also be classified by their material, with common types being glass, silicon, and various polymers like PDMS

Microfluidic Chips Application and Function

Organ-on-a Chip (OAC)

Devices that mimic the function of human organs to model diseases and test drugs.

Microfluidic Cell Sorters

Used to sort and separate cells based on characteristics like size or fluorescence, crucial for research and diagnostics.

Microfluidic Mixers

Engineered to rapidly and efficiently mix small volumes of fluids for biochemical reactions.

Lab-on-a-Chip (LOC)

Integrates multiple laboratory functions (like PCR or chemical assays) onto a single chip for high-throughput applications.

Diagnostics Chips

Devices for point-of-care diagnostics or assays, such as microfluidic PCR or electrochemical sensors.

Microfluidic Chip Fluid Handling Methods

Continuous-Flow Microfluidics

Fluids are pumped continuously through microchannels for tasks like mixing, chemical reactions, and separations.

Digital (droplet-based) Microfluidics

Liquids are handled as discrete, digitized droplets that are precisely moved and manipulated across a surface, often using electrical fields.

Paper-Based Microfluidics

Fluids are absorbed and transported through paper, enabling low-cost, disposable diagnostic tools that function similarly to a lateral flow test.

Microfluidic Chip Materials

Glass and Silicon

These were the original materials used for microfluidics due to their established manufacturing processes.

Polymers

Including materials like PDMS (polydimethylsiloxane), polycarbonate, and other plastics, often chosen for their lower cost and ease of use.

Paper

Used for very low-cost, disposable devices

Precision Laser Cutting
Complex Rotary Die Cutting
Assembly and Packaging

Microfluidics Converting and Assembly

Microfluidic devices are often made by constructing or stacking layers of components, with different internal geometries and properties. For example, channels created by gapping between layers may allow for blood or fluid flow. In these applications registration between layers must be accurate and precise. Converting machines often have sensors that detect registration marks or “eye marks” that affirm laminates are aligned before laminating. Lamination of multiple components also requires edge guiding and proper laminator setup.

Rotary Die Cutting

Rotary die cutting is a common method in microfluidic device converting. Hi-Tech Products offers precision rotary die cutting on state-of-the-art servo controlled presses with electronic registration. With an average of over 10 years experience, our medical die cutting specialists are trained to operate the most sophisticated equipment available and have developed unique processes unavailable anywhere else.

Precision Laser Cutting

Laser cutting is also common in microfluidic chip converting. In microfluidic device converting, lasers facilitate very intricate cuts or can be used to “drill” holes in a component. Lasers are often used in test strip converting to cut tiny conduits and vents that channel precise amounts of liquids or vapors. See more about precision laser cutting.

Hi-Tech Products – Your Microfluidic Chip and Device Manufacturing Partner…

Hi-Tech Products offers precision laser cutting, rotary die cutting, converting, as well as assembly and packaging in certified clean rooms. Our Factories in the US and Mexico provide American engineered quality at offshore pricing. Hi-Tech Products is FDA registered, ISO 13485:2016, and ISO 9001:2015 certified.

Diagnostics and Microfluidics Materials Considerations

Materials Properties

• Low Fluorescence

• Caliper Tolerances

• Light Transmission Spectra

• Clarity or Haze

• Solvent Resistance

Compatibility

• Biocompatibility

• Thermo Stability

• Chemically Inert

• Assay Compatible

Manufacturability

• Die Cutting

• Quality Uniformity Control

• Traceability

• Manufacturing to Scale

• Change management

Complex Rotary Die Cutting and Precision Laser Processing Performed in Certified Cleanrooms.

Equipped with over 30 rotary presses and precision laser equipment in the US and Mexico, Hi Tech Products is fully equipped for your microfluidics components manufacturing. Hi-Tech Products is able to offer the highest quality components and American engineering at offshore pricing. Hi-Tech Product’s facilities are FDA registered, ISO 13485:2016 and ISO 9001:2015 Certified. Medical device assembly and packaging is done in our Tijuana Mexico facility with American engineered quality–offering the benefit of offshore pricing in class 100,000 clean rooms.